Expert Perspectives

Deep dives into cell therapy partnerships, Japan market entry, and strategic execution.

Investment

Valuation of Early-Stage Assets in 2025

December 10, 2025

How interest rates and geopolitical shifts are affecting asset pricing in cross-border deals.

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Cell Therapy Strategy

The Integration Edge

January 13, 2025

The semiconductor industry learned that vertical integration of design and manufacturing creates sustainable competitive advantage. Cell therapy is learning the same lesson.

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Cell Therapy Strategy

Three Manufacturing Strategies That Work

January 20, 2025

In-house manufacturing, CDMO partnerships, or strategic manufacturing alliances—the right choice depends on your stage, volume trajectory, and differentiation strategy.

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Cell Therapy Strategy

Platform vs. Product

January 27, 2025

Platform acquisitions and product acquisitions require fundamentally different valuation approaches. Getting this distinction wrong leads to either overpaying for products or undervaluing platforms.

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Cell Therapy Strategy

Cell Therapy Partnership Strategy

January 6, 2025

A comprehensive guide to cell therapy partnerships, covering manufacturing integration, deal structures, technology evolution, and strategic entry frameworks.

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Cell Therapy Strategy

What the Best Cell Therapy Partnerships Have in Common

January 6, 2025

Five characteristics consistently appear in cell therapy partnerships that succeed: manufacturing mastery, platform value recognition, cost trajectory alignment, stage-appropriate structures, and geographic complementarity.

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Cell Therapy Strategy

Speed-to-Patient as Competitive Advantage

February 3, 2025

Manufacturing time affects T-cell phenotype, patient access, and commercial economics. Speed-to-patient is emerging as the critical differentiator in cell therapy competition.

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Cell Therapy Strategy

CAR-T Generations: A Practical Guide for Strategic Acquirers

February 10, 2025

Generation number is less predictive of clinical success than specific design choices. This guide provides a framework for evaluating next-generation claims.

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Cell Therapy Strategy

Solid Tumor CAR-T

February 17, 2025

Solid tumor CAR-T represents the highest-risk, highest-potential opportunity in cell therapy. Regional delivery and tumor microenvironment engineering are showing early signals of activity.

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Cell Therapy Strategy

Beyond Autologous

February 24, 2025

Autologous CAR-T dominates today, but allogeneic, CAR-NK, and in vivo platforms offer portfolio diversification for strategic acquirers evaluating cell therapy entry.

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Cell Therapy Strategy

Deal Architectures from Landmark Partnerships

March 3, 2025

From Legend-Janssen profit-sharing to AstraZeneca-Gracell platform acquisition, the deal structures that succeed share common elements of risk allocation and incentive alignment.

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Cell Therapy Strategy

Strategic Entry Points for New Cell Therapy Acquirers

March 10, 2025

Cell therapy is not a closed market. New targets, manufacturing innovations, geographic opportunities, and modality evolution continue to create entry points for thoughtful latecomers.

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Market Entry

Navigating the Japan Biopharma Market: A Strategic Guide

January 15, 2024

Why entering Japan requires more than just translation. Understanding the regulatory and cultural nuances.

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